Setting up your On Cloudrunner 2 Waterproof shoes involves simply lacing them up to achieve a comfortable, secure fit. They are compatible with a wide range of athletic activities, from road running to light trail work, and are particularly well-suited for use in wet weather. For care, it's recommended to clean off mud and dirt gently after each use. For deeper cleaning, use a soft brush and mild soap with cold water, avoiding harsh chemicals or machine washing to preserve the waterproof membrane and material integrity. Allow them to air dry naturally, away from direct heat sources. Regular cleaning helps maintain their performance and prolong their lifespan.